According to the World Health Organisation (WHO), the number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014. Over the same period, the global prevalence of diabetes among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014.

 

"diabetes has risen from 108 million"

 

Diabetes prevalence has been rising more rapidly in middle- and low-income countries. The disease is a major cause of blindness, kidney failure, heart attacks, stroke and lower limb amputation.

These epidemics of obesity and diabetes contribute to development of no-communicable diseases (NCDs), the foremost cause of death globally, leading to more deaths each year than all other diseases combined (WHO, 2012). We have even underestimated the diabetes rate: 347 million adult diabetics in 2008 already exceeded the 285 million estimated for 2010 (Shaw et al., 2009; Danaei et al.,2011). Cardiovascular disease kills almost double the amount of diabetics compared to the general population (Peters et al., 2014).

The complexity of these metabolic diseases makes proper treatment of the underlying causes very difficult. (Tiwari and Rao, 2002).

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The challenge is to unlock the potential of traditionally used African botanicals as a novel therapeutic herbal treatment – Afriplex GRT ™ goes a long way in achieving this objective.

 

MECHANISM

 

South African Medical Research Council highlights the potential of ROOIBOS to prevent metabolic syndrome. It has been shown to alleviate insulin resistance, enhance glucose uptake, and to balance lipid dysregulation (Kawano et al, 2009; Muller et al, 2012; Kamakuru et al, 2014; Mazibuko, 2014). Aspalathin protects vulnerable cells, such as insulin producing pancreatic β-cells, against increased oxidative stress and inflammation linked to an unhealthy diet, insulin resistance and obesity (Son et al, 2012; Kamakura et al, 2014; Himpe et al, 2016).

 

"prevent metabolic syndrome"

 

 

In a Japanese study it was similarly found that Aspalathin increased glucose uptake and insulin secretion and was effective in reducing hyperglycaemia and glucose intolerance in mice (Li et al, 2009). Further work has shown that it could provide protection to the diabetic heart (Johnson, 2016). More research has shown that the Aspalathus linearis plant has potent antioxidant and anti-mutagenic activities, and that it also possesses potent immune-modulating and chemo-preventive actions (McKay & Blumberg, 2007).

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